Diabesity - novel molecular targets for obesity and type 2 diabetes
 
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Publications 2008
The following 89 publications have arisen from DIABESITY in 2008:

Protein components of the blood-brain barrier (BBB) in the brainstem area postrema-nucleus tractus solitarius region
N Maolood and B Meister
J Chem Neuroanat (2008)

Mice with Hyperghrelinemia are Hyperphagic, Glucose Intolerant and have Reduced Leptin Sensitivity
GA Bewick, A Kent, D Campbell, M Patterson, MA Ghatei, SR Bloom and JV Gardiner
Diabetes (2009)

Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion
MM Gonzalez-Barroso, I Giurgea, F Bouillaud, A Anedda, C Bellanne-Chantelot, L Hubert, Y de Keyzer, P de Lonlay and D Ricquier
PLoS ONE (2008) 3:e3850

Beta adrenergic aGONISM does not impair the GH response to acylated ghrelin in man
A Benso, E Gramaglia, F Prodam, F Riganti, VR Gigliardi, B Lucatello, I Olivetti, D St Pierre, E Ghigo and F Broglio
Clin Endocrinol (Oxf) (2008)

Temporal profile of estrogen-dependent gene expression in LHRH-producing GT1-7 cells
P Varju, KC Chang, E Hrabovszky, I Merchenthaler and Z Liposits
Neurochem Int (2008)

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
CJ Willer, EK Speliotes, RJ Loos, S Li, CM Lindgren, IM Heid, SI Berndt, AL Elliott, AU Jackson, C Lamina, G Lettre, N Lim, HN Lyon, SA McCarroll, K Papadakis, L Qi, JC Randall, RM Roccasecca, S Sanna, P Scheet, MN Weedon, E Wheeler, JH Zhao, LC Jacobs, I Prokopenko, N Soranzo, T Tanaka, NJ Timpson, P Almgren, A Bennett, RN Bergman, SA Bingham, LL Bonnycastle, M Brown, NP Burtt, P Chines, L Coin, FS Collins, JM Connell, C Cooper, GD Smith, EM Dennison, P Deodhar, P Elliott, MR Erdos, K Estrada, DM Evans, L Gianniny, C Gieger, CJ Gillson, C Guiducci, R Hackett, D Hadley, AS Hall, AS Havulinna, J Hebebrand, A Hofman, B Isomaa, KB Jacobs, T Johnson, P Jousilahti, Z Jovanovic, KT Khaw, P Kraft, M Kuokkanen, J Kuusisto, J Laitinen, EG Lakatta, J Luan, RN Luben, M Mangino, WL McArdle, T Meitinger, A Mulas, PB Munroe, N Narisu, AR Ness, K Northstone, S O'Rahilly, C Purmann, MG Rees, M Ridderstrale, SM Ring, F Rivadeneira, A Ruokonen, MS Sandhu, J Saramies, LJ Scott, A Scuteri, K Silander, MA Sims, K Song, J Stephens, S Stevens, HM Stringham, YC Tung, TT Valle, CM Van Duijn, KS Vimaleswaran, P Vollenweider, G Waeber, C Wallace, RM Watanabe, DM Waterworth, N Watkins, JC Witteman, E Zeggini, G Zhai, MC Zillikens, D Altshuler, MJ Caulfield, SJ Chanock, IS Farooqi, L Ferrucci, JM Guralnik, AT Hattersley, FB Hu, MR Jarvelin, M Laakso, V Mooser, KK Ong, WH Ouwehand, V Salomaa, NJ Samani, TD Spector, T Tuomi, J Tuomilehto, M Uda, AG Uitterlinden, NJ Wareham, P Deloukas, TM Frayling, LC Groop, RB Hayes, DJ Hunter, KL Mohlke, L Peltonen, D Schlessinger, DP Strachan, HE Wichmann, MI McCarthy, M Boehnke, I Barroso, GR Abecasis and JN Hirschhorn
Nat Genet (2009) 41:25-34

Photoperiod regulates genes encoding melanocortin 3 and serotonin receptors and secretogranins in the dmpARC of the Siberian hamster
KN Nilaweera, ZA Archer, G Campbell, CD Mayer, A Balik, AW Ross, JG Mercer, FJ Ebling, PJ Morgan and P Barrett
J Neuroendocrinol (2008)

Investigation of Structure-Activity Relationships of Oxyntomodulin using Oxyntomodulin analogues
MR Druce, JS Minnion, BC Field, SR Patel, J Cuenco-Shilito, M Tilby, KE Beale, KG Murphy, MA Ghatei and SR Bloom
Endocrinology (2008)

Association of the MC4R V103I polymorphism with the metabolic syndrome: the KORA Study
IM Heid, C Vollmert, F Kronenberg, C Huth, DP Ankerst, A Luchner, A Hinney, G Brönner, HE Wichmann, T Illig, A Doring and J Hebebrand
Obesity (Silver Spring) (2008) 16:369-376

Differential patterns of neuronal activation in the brainstem and hypothalamus following peripheral injection of GLP-1, oxyntomodulin and lithium chloride in mice detected by manganese-enhanced magnetic resonance imaging (MEMRI)
JR Parkinson, OB Chaudhri, YT Kuo, BC Field, AH Herlihy, WS Dhillo, MA Ghatei, SR Bloom and JD Bell
Neuroimage (2008)

Lifestyle Intervention in Obese Children With Variations in the Melanocortin 4 Receptor Gene
T Reinehr, J Hebebrand, S Friedel, AM Toschke, H Brumm, H Biebermann and A Hinney
Obesity (Silver Spring) (2008)

Increased constraints on MC4R during primate and human evolution
DA Hughes, A Hinney, H Brumm, AK Wermter, H Biebermann, J Hebebrand and M Stoneking
Hum Genet (2008)

Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa
TD Müller, K Reichwald, G Brönner, J Kirschner, TT Nguyen, A Scherag, W Herzog, B Herpertz-Dahlmann, P Lichtner, T Meitinger, M Platzer, H Schafer, J Hebebrand and A Hinney
Child Adolesc Psychiatry Ment Health (2008) 2:33

Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial
A Astrup, S Madsbad, L Breum, TJ Jensen, JP Kroustrup and TM Larsen
Lancet (2008)
Press release from Lancet

Larrad Biliopancreatic Diversion in Sprague-Dawley Rats. Analysis of Weight Loss Related to Food Intake
H Mendieta-Zerón, A Larrad-Jimónez, G Frühbeck, K Da Boit and C Diéguez
Obes Surg (2008)

The role and regulation of 11beta-hydroxysteroid dehydrogenase type 1 in the inflammatory response
KE Chapman, AE Coutinho, M Gray, JS Gilmour, JS Savill and JR Seckl
Mol Cell Endocrinol (2008)

AMPK: a metabolic gauge regulating whole-body energy homeostasis
R Lage, C Diéguez, A Vidal-Puig and M López
Trends Mol Med (2008)

Influence of chronic undernutrition and leptin on GOAT mRNA levels in rat stomach mucosa
C González, M Vázquez, M López and C Diéguez
J Mol Endocrinol (2008)

Type 1 cannabinoid receptor (CB1)-containing axons innervate hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons
L Deli, G Wittmann, I Kalló, RM Lechan, M Watanabe, Z Liposits and C Fekete
Endocrinology (2008)

'Fat mass and obesity associated' gene (FTO): no significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents
TD Müller, A Hinney, A Scherag, TT Nguyen, F Schreiner, H Schäfer, J Hebebrand, CL Roth and T Reinehr
BMC Med Genet (2008) 9:85

Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study
P Linsel-Nitschke, A Götz, J Erdmann, I Braenne, P Braund, C Hengstenberg, K Stark, M Fischer, S Schreiber, NE El Mokhtari, A Schaefer, J Schrezenmeier, D Rubin, A Hinney, T Reinehr, C Roth, J Ortlepp, P Hanrath, AS Hall, M Mangino, W Lieb, C Lamina, IM Heid, A Doering, C Gieger, A Peters, T Meitinger, HE Wichmann, IR König, A Ziegler, F Kronenberg, NJ Samani and H Schunkert
PLoS ONE (2008) 3:e2986

Peripheral, but not central, CB1 antagonism provides food intake independent metabolic benefits in diet-induced obese rats
R Nogueiras, C Veyrat-Durebex, PM Suchanek, M Klein, J Tschöp, C Caldwell, SC Woods, G Wittmann, M Watanabe, Z Liposits, C Fekete, O Reizes, F Rohner-Jeanrenaud and MH Tschöp
Diabetes (2008)

Overexpression of CART in the PVN Increases Food Intake and Weight Gain in Rats
KL Smith, JV Gardiner, HL Ward, WM Kong, KG Murphy, NM Martin, MA Ghatei and SR Bloom
Obesity (2008)

The effects of pancreatic polypeptide on locomotor activity and food intake in mice
YL Liu, NM Semjonous, KG Murphy, MA Ghatei and SR Bloom
Int J Obes (Lond) (2008)

A new method of spike modelling and interval analysis
DJ Macgregor, CK Williams and G Leng
J Neurosci Methods (2008)

Evidence for an influence of TCF7L2 polymorphism rs7903146 on insulin resistance and sensitivity indices in overweight children and adolescents during a lifestyle intervention
T Reinehr, S Friedel, TD Mueller, AM Toschke, J Hebebrand and A Hinney
Int J Obes (Lond) (2008)

Oestrogen receptor alpha and beta immunoreactive cells in the suprachiasmatic nucleus of mice: distribution, sex differences and regulation by gonadal hormones
B Vida, E Hrabovszky, T Kalamatianos, CW Coen, Z Liposits and I Kalló
J Neuroendocrinol (2008)

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G >C with circulating glucose levels, interleukin-6 levels, and body mass index
C Huth, T Illig, C Herder, C Gieger, H Grallert, C Vollmert, W Rathmann, YH Hamid, O Pedersen, T Hansen, B Thorand, C Meisinger, A Döring, N Klopp, H Gohlke, W Lieb, C Hengstenberg, V Lyssenko, L Groop, H Ireland, JW Stephens, I Wernstedt Asterholm, JO Jansson, H Boeing, M Mohlig, HM Stringham, M Boehnke, J Tuomilehto, JM Fernandez-Real, A Lopez-Bermejo, L Gallart, J Vendrell, SE Humphries, F Kronenberg, HE Wichmann and IM Heid
Ann Med (2008) 1-21

Population-specific risk of type 2 diabetes (T2D) conferred by HNF4A P2 promoter variants: a lesson for replication studies
I Barroso, J Luan, E Wheeler, P Whittaker, J Wasson, E Zeggini, MN Weedon, S Hunt, R Venkatesh, TM Frayling, M Delgado, RJ Neuman, J Zhao, R Sherva, B Glaser, M Walker, G Hitman, MI McCarthy, AT Hattersley, MA Permutt, NJ Wareham and P Deloukas
Diabetes (2008)

Monogenic polycystic ovary syndrome due to a mutation in the lamin A/C gene is sensitive to thiazolidinediones but not to metformin
A Gambineri, RK Semple, G Forlani, S Genghini, I Grassi, CS Hyden, U Pagotto, S O'Rahilly and R Pasquali
Eur J Endocrinol (2008) 159:347-353

Regulation of cocaine-and amphetamine-regulated transcript-(CART) synthesising neurones of the hypothalamic paraventricular nucleus by endotoxin; Implications for LPS-induced regulation of energy homeostasis
T Füzesi, E Sánchez, G Wittmann, PS Singru, C Fekete and RM Lechan
J Neuroendocrinol (2008)

Mutations in the N-Terminal Region of Pro-Opiomelanocortin (Pomc) in Patients with Early-Onset Obesity Impair Pomc Sorting to the Regulated Secretory Pathway
JW Creemers, YS Lee, RL Oliver, M Bahceci, A Tuzcu, D Gokalp, J Keogh, S Herber, A White, S O'Rahilly and IS Farooqi
J Clin Endocrinol Metab (2008)

Kisspeptins and the control of gonadotropin secretion in humans
CN Jayasena, WS Dhillo and SR Bloom
Peptides (2008)

The thyroid hormone derivative 3-iodothyronamine increases food intake in rodents
WS Dhillo, GA Bewick, NE White, JV Gardiner, EL Thompson, A Bataveljic, KG Murphy, D Roy, NA Patel, JN Scutt, A Armstrong, MA Ghatei and SR Bloom
Diabetes Obes Metab (2008)

Spontaneous discharge characteristic of neurons in the ventromedial nucleus of the rat hypothalamus in vivo
N Sabatier and G Leng
Eur J Neurosci (2008)

Glucocorticoid regulation of the promoter of 11{beta}-hydroxysteroid dehydrogenase type 1 is indirect and requires C/EBP{beta}
S Sai, CL Esteves, V Kelly, Z Michailidou, K Anderson, AP Coll, Y Nakagawa, T Ohzeki, JR Seckl and KE Chapman
Mol Endocrinol (2008)

Protein components of the blood-brain barrier (BBB) in the mediobasal hypothalamus
E Norsted, B Gömüç and B Meister
J Chem Neuroanat (2008)

FOXC2 controls Ang-2 expression and modulates angiogenesis, vascular patterning, remodeling, and functions in adipose tissue
Y Xue, R Cao, D Nilsson, S Chen, R Westergren, EM Hedlund, C Martijn, L Rondahl, P Krauli, E Walum, S Enerbäck and Y Cao
Proc Natl Acad Sci U S A (2008) 105:10167-10172

No evidence of an additive inhibitory feeding effect following PP and PYY(3-36) administration
NM Neary, BM McGowan, MP Monteiro, DR Jesudason, MA Ghatei and SR Bloom
Int J Obes (Lond) (2008)

The regulation of seasonal changes in food intake and body weight
FJ Ebling and P Barrett
J Neuroendocrinol (2008) 20:827-833

Novel aspects of glutamatergic signalling in the neuroendocrine system
E Hrabovszky and Z Liposits
J Neuroendocrinol (2008) 20:743-751

Evaluating the role of LPIN1 variation on insulin resistance, body weight and human lipodystrophy in UK populations
KA Fawcett, N Grimsey, RJ Loos, E Wheeler, A Daly, M Soos, R Semple, H Syddall, C Cooper, S Siniossoglou, S O'Rahilly, NJ Wareham and I Barroso
Diabetes (2008)

Acetylated ghrelin inhibits spontaneous LH pulsatility and responsiveness to Naloxone, but not that to GnRH in young men: evidence for at central inhibitory action of ghrelin in the gonadal axis
F Lanfranco, L Bonelli, M Baldi, E Me, F Broglio and E Ghigo
J Clin Endocrinol Metab (2008)

Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha
H Duez, JV Veen, C Duhem, B Pourcet, T Touvier, C Fontaine, B Derudas, E Baugé, R Havinga, VW Bloks, H Wolters, FH van der Sluijs, B Vennström, F Kuipers and B Staels
Gastroenterology (2008)

The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism
H Duez and B Staels
Diab Vasc Dis Res (2008) 5:82-88

QRFP43 stimulates the hypothalamic-pituitary-gonadal axis via GnRH in rats
SR Patel, KG Murphy, EL Thompson, M Patterson, AE Curtis, MA Ghatei and SR Bloom
Endocrinology (2008)

The nuclear receptor Rev-erb{alpha} is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages
C Fontaine, E Rigamonti, B Pourcet, H Duez, C Duhem, JC Fruchart, G Chinetti-Gbaguidi and B Staels
Mol Endocrinol (2008)

Relaxin-3 stimulates the hypothalamic-pituitary-gonadal axis
BM McGowan, SA Stanley, J Donovan, EL Thompson, M Patterson, NM Semjonous, JV Gardiner, K Murphy, MA Ghatei and SR Bloom
Am J Physiol Endocrinol Metab (2008)

Central resistin regulates hypothalamic and peripheral lipid metabolism in a nutritional dependent fashion
MJ Vázquez, CR González, L Varela, R Lage, S Tovar, S Sangiao-Alvarellos, LM Williams, A Vidal-Puig, R Nogueiras, M López and C Diéguez
Endocrinology (2008)

The role of the transcription factor Sox4 in insulin secretion and impaired glucose tolerance
M Goldsworthy, A Hugill, H Freeman, E Horner, K Shimomura, D Bogani, G Pieles, V Mijat, R Arkell, S Bhattacharya, FM Ashcroft and RD Cox
Diabetes (2008)

Activation of Stat3 signaling in AgRP neurons promotes locomotor activity
A Mesaros, SB Koralov, E Rother, FT Wunderlich, MB Ernst, GS Barsh, K Rajewsky and JC Brüning
Cell Metab (2008) 7:236-248

Central insulin action regulates peripheral glucose and fat metabolism in mice
L Koch, FT Wunderlich, J Seibler, AC Könner, B Hampel, S Irlenbusch, G Brabant, CR Kahn, F Schwenk and JC Brüning
J Clin Invest (2008)

PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response
BF Belgardt, A Husch, E Rother, MB Ernst, FT Wunderlich, B Hampel, T Klöckener, D Alessi, P Kloppenburg and JC Brüning
Cell Metab (2008) 7:291-301

Dynorphin in pro-opiomelanocortin neurons of the hypothalamic arcuate nucleus
N Maolood and B Meister
Neuroscience (2008)

Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through eNOS expression in white adipocytes
L Tedesco, A Valerio, C Cervino, A Cardile, C Pagano, R Vettor, R Pasquali, MO Carruba, G Marsicano, B Lutz, U Pagotto and E Nisoli
Diabetes (2008)

11beta-HSD1, inflammation, metabolic disease and age-related cognitive (dys)function
KE Chapman and JR Seckl
Neurochem Res (2008) 33:624-636

Hypothalamic thyroid hormone in energy balance regulation
A Herwig, AW Ross, KN Nilaweera, PJ Morgan and P Barrett
Obes Facts 2008;1:2-2

Here, there and everywhere: the endocannabinoid system
R Vettor, U Pagotto, C Pagano and R Pasquali
J Neuroendocrinol (2008) 20 Suppl 1:iv-vi

Common variants near MC4R are associated with fat mass, weight and risk of obesity
RJ Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, M Inouye, RM Freathy, AP Attwood, JS Beckmann, SI Berndt, KB Jacobs, SJ Chanock, RB Hayes, S Bergmann, AJ Bennett, SA Bingham, M Bochud, M Brown, S Cauchi, JM Connell, C Cooper, GD Smith, I Day, C Dina, S De, ET Dermitzakis, AS Doney, KS Elliott, P Elliott, DM Evans, I Sadaf Farooqi, P Froguel, J Ghori, CJ Groves, R Gwilliam, D Hadley, AS Hall, AT Hattersley, J Hebebrand, IM Heid, C Lamina, C Gieger, T Illig, T Meitinger, HE Wichmann, B Herrera, A Hinney, SE Hunt, MR Jarvelin, T Johnson, JD Jolley, F Karpe, A Keniry, KT Khaw, RN Luben, M Mangino, J Marchini, WL McArdle, R McGinnis, D Meyre, PB Munroe, AD Morris, AR Ness, MJ Neville, AC Nica, KK Ong, S O'Rahilly, KR Owen, CN Palmer, K Papadakis, S Potter, A Pouta, L Qi, P Kraft, SE Hankinson, DJ Hunter, FB Hu, JC Randall, NW Rayner, SM Ring, MS Sandhu, A Scherag, MA Sims, K Song, N Soranzo, EK Speliotes, HN Lyon, BF Voight, M Ridderstrale, L Groop, HE Syddall, SA Teichmann, NJ Timpson, JH Tobias, M Uda, P Scheet, S Sanna, GR Abecasis, G Albai, R Nagaraja, D Schlessinger, CI Ganz Vogel, C Wallace, DM Waterworth, MN Weedon, CJ Willer, AU Jackson, J Tuomilehto, FS Collins, M Boehnke, KL Mohlke, VL Wraight, X Yuan, E Zeggini, JN Hirschhorn, DP Strachan, WH Ouwehand, MJ Caulfield, NJ Samani, TM Frayling, P Vollenweider, G Waeber, V Mooser, P Deloukas, MI McCarthy, NJ Wareham and I Barroso
Nat Genet (2008)

The Human Lipodystrophy Gene BSCL2/Seipin May Be Essential For Normal Adipocyte Differentiation
VA Payne, N Grimsey, A Tuthill, S Virtue, SL Gray, ED Nora, RK Semple, S O'Rahilly and JJ Rochford
Diabetes (2008)

Hypothalamic Fatty Acid Metabolism Mediates the Orexigenic Action of Ghrelin
M López, R Lage, AK Saha, D Pérez-Tilve, MJ Vázquez, L Varela, S Sangiao-Alvarellos, S Tovar, K Raghay, S Rodriguez-Cuenca, RM Deoliveira, T Castañeda, R Datta, JZ Dong, M Culler, MW Sleeman, CV Álvarez, R Gallego, CJ Lelliott, D Carling, MH Tschöp, C Diéguez and A Vidal-Puig
Cell Metab (2008) 7:389-399

Cannabinoid type 1 receptor: another arrow in the adipocytes' bow
L Bellocchio, C Cervino, V Vicennati, R Pasquali and U Pagotto
J Neuroendocrinol (2008) 20 Suppl 1:130-138

The thyrotropin-releasing hormone secretory system in the hypothalamus of the Siberian hamster in long and short photoperiods
FJP Ebling, D Wilson, J Wood, D Hughes, JG Mercer, PJ Morgan and P Barrett
J Neuroendocrinol (2008) 20:576-586

Preferential reciprocal transfer of paternal/maternal DLK1 alleles to obese children: first evidence of polar overdominance in humans
AK Wermter, A Scherag, D Meyre, K Reichwald, E Durand, TT Nguyen, K Koberwitz, P Lichtner, T Meitinger, H Schäfer, A Hinney, P Froguel, J Hebebrand and G Brönner
Eur J Hum Genet (2008)

Food intake regulating-neuropeptides are expressed and regulated through pregnancy and following food restriction in rat placenta
JE Caminos, SB Bravo, CR González, MF Garcés, LA Cepeda, AC González, F Cordido, M López and C Diéguez
Reprod Biol Endocrinol (2008) 6:14

Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors are involved in mediating the ghrelin-induced locomotor stimulation and dopamine overflow in nucleus accumbens
E Jerlhag, E Egecioglu, SL Dickson, L Svensson and JA Engel
Eur Neuropsychopharmacol (2008)

The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system
B Kola, I Farkas, M Christ-Crain, G Wittmann, F Lolli, F Amin, J Harvey-White, Z Liposits, G Kunos, AB Grossman, C Fekete and M Korbonits
PLoS ONE (2008) 3:e1797

Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders
JM Mercader, E Saus, Z Agüera, M Bayes, C Boni, A Carreras, E Cellini, R de Cid, M Dierssen, G Escaramís, F Fernández-Aranda, L Forcano, X Gallego, JR Gonzàlez, P Gorwood, J Hebebrand, A Hinney, B Nacmias, A Puig, M Ribasés, V Ricca, L Romo, S Sorbi, A Versini, M Gratacòs and X Estivill
Hum Mol Genet (2008) 17:1234-1244

Cortistatin-8, a synthetic cortistatin-derived ghrelin receptor ligand, does not modify the endocrine responses to acylated ghrelin or hexarelin in humans
F Prodam, A Benso, E Gramaglia, B Lucatello, F Riganti, AJ van der Lely, R Deghenghi, G Muccioli, E Ghigo and F Broglio
Neuropeptides (2008) 42:89-93

Association of a homozygous nonsense Caveolin-1 mutation with Berardinelli-Seip Congenital Lipodystrophy
CA Kim, M Delépine, E Boutet, H El Mourabit, S Le Lay, M Meier, M Nemani, E Bridel, CC Leite, DR Bertola, RK Semple, S O'Rahilly, I Dugail, J Capeau, M Lathrop and J Magré
J Clin Endocrinol Metab (2008) 93:1129-1134

Elevated cocaine- and amphetamine-regulated transcript (CART)-immunoreactivity in the circulation of patients with neuroendocrine malignancy
P Bech, V Winstanley, KG Murphy, AH Sam, K Meeran, MA Ghatei and SR Bloom
J Clin Endocrinol Metab (2008) 93:1246-1253

Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability
R Nogueiras, M López, R Lage, D Perez-Tilve, P Pfluger, H Mendieta-Zerón, M Sakkou, P Wiedmer, S Benoit, R Datta, JZ Dong, M Culler, M Sleeman, A Vidal-Puig, T Horvath, M Treier, C Diéguez and MH Tschöp
Endocrinology (2008)

Preanalytical factors affecting RIA measurement of plasma Kisspeptin
R Ramachandran, M Patterson, KG Murphy, WS Dhillo, S Patel, A Kazarian, MA Ghatei and SR Bloom
Clin Chem (2008) 54:615-617

Effects of leptin on energy metabolism in beta-less mice
CS Asensio, D Arsenijevic, L Lehr, JP Giacobino, P Muzzin and F Rohner-Jeanrenaud
Int J Obes (Lond) (2008)

DHEA induces 11 -HSD2 by acting on CCAAT/enhancer-binding proteins
Z Balazs, RA Schweizer, FJ Frey, F Rohner-Jeanrenaud and A Odermatt
J Am Soc Nephrol (2008) 19:92-101

A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population

A Benrick, P Jirholt, I Wernstedt, M Gustafsson, J Scheller, AL Eriksson, J Borén, T Hedner, C Ohlsson, T Härd, S Rose-John and JO Jansson
Regul Pept (2008) 146:189-196

Rev-erb alpha gives a time cue to metabolism
H Duez and B Staels
FEBS Lett (2008) 582:19-25

Hypothalamic gene expression following ghrelin therapy to gastrectomized rodents
E Egecioglu, B Stenström, SB Pinnock, LY Tung, C Dornonville de la Cour, A Lindqvist, R Håkanson, U Syversen, D Chen and SL Dickson
Regul Pept (2008) 146:176-182

Diurnal profiles of hypothalamic energy balance gene expression with photoperiod manipulation in the Siberian hamster, Phodopus sungorus
C Ellis, KM Moar, TJ Logie, AW Ross, PJ Morgan and JG Mercer
Am J Physiol Regul Integr Comp Physiol (2008) 294:R1148-1153

Estrogen enhances expression of the complement C5a receptor and the C5a-agonist evoked calcium influx in hormone secreting neurons of the hypothalamus
I Farkas, P Varju, E Szabo, E Hrabovszky, N Okada, H Okada and Z Liposits
Neurochem Int (2008) 52:846-856

Feeding Behavior in Rats Subjected to Gastrectomy or Gastric Bypass Surgery
MW Furnes, B Stenström, K Tømmerås, T Skoglund, SL Dickson, B Kulseng, CM Zhao and D Chen
Eur Surg Res (2008) 40:279-288

Immunohistochemical and in situ hybridization studies on glycine transporter 1 after transient ischemia in the rat forebrain
I Kalló, C Jekkel, E Hrabovszky, Z Jurányi, B Vida, A Járási, T Wilheim, LG Harsing, Jr. and Z Liposits
Neurochem Int (2008) 52:799-808

Neurocircuits integrating hormone and nutrient signaling in control of glucose metabolism
E Rother, AC Könner and J Brüning
Am J Physiol Endocrinol Metab (2008)

LDL-cholesterol concentrations: a genome-wide association study
MS Sandhu, DM Waterworth, SL Debenham, E Wheeler, K Papadakis, JH Zhao, K Song, X Yuan, T Johnson, S Ashford, M Inouye, R Luben, M Sims, D Hadley, W McArdle, P Barter, YA Kesaniemi, RW Mahley, R McPherson, SM Grundy, SA Bingham, KT Khaw, RJ Loos, G Waeber, I Barroso, DP Strachan, P Deloukas, P Vollenweider, NJ Wareham and V Mooser
Lancet (2008) 371:483-491

Cholinergic afferents to gonadotropin-releasing hormone neurons of the rat
GF Turi, Z Liposits and E Hrabovszky
Neurochem Int (2008) 52:723-728

IL6 and IL1B Polymorphisms are Associated With Fat Mass in Older Men: The MrOS Study Sweden
L Strandberg, D Mellström, Ö Ljunggren, E Grundberg, MK Karlsson, AH Holmberg, ES Orwoll, AL Eriksson, J Svedberg, M Bengtsson, C Ohlsson and JO Jansson
Obesity (Silver Spring) (2008) 16:710-713

PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism
M Vinciguerra, C Veyrat-Durebex, MA Moukil, L Rubbia-Brandt, F Rohner-Jeanrenaud and M Foti
Gastroenterology (2008) 134:268-280

Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization
C Pecqueur, T Bui, C Gelly, J Hauchard, C Barbot, F Bouillaud, D Ricquier, B Miroux and CB Thompson
FASEB J (2008) 22:9-18

Modified glutamine catabolism in macrophages of Ucp2 knock-out mice
T Nübel, Y Emre, D Rabier, B Chadefaux, D Ricquier and F Bouillaud
Biochim Biophys Acta (2008) 1777:48-54

Diabesity: Novel molecular targets for obesity and type 2 diabetes
   
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